Journal
HEART FAILURE REVIEWS
Volume 10, Issue 2, Pages 95-100Publisher
SPRINGER
DOI: 10.1007/s10741-005-4636-y
Keywords
left ventricular remodeling; wall stress; stretch; heart failure
Categories
Funding
- NHLBI NIH HHS [R01 HL58081-01, R01 HL61543-01, P50 HL-O6H, HL-42250-10/10] Funding Source: Medline
Ask authors/readers for more resources
Heart failure may be viewed as a progressive disorder that is impelled, at least in part, by progressive left ventricular (LV) remodeling. In the present discussion we will review the role of LV remodeling in the pathogenesis of heart failure, with a focus on the contribution that changes in LV size and shape play in the development and progression of the progression of heart failure. The clinical implication of this review is that existing neurohormonal strategies may not completely prevent disease progression in the failing heart, and that adjunctive strategies that are designed to specifically prevent and/or attenuate LV remodeling may play an important role in the clinical treatment of heart failure.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available