Journal
PROTEOMICS
Volume 5, Issue 9, Pages 2381-2384Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/pmic.200401244
Keywords
analysis; liquid chromatography; mass spectrometry; proteome imaging; software
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images obtained from high-throughput mass spectrometry (MS) contain information that remains hidden when looking at a single spectrum at a time. Image processing of liquid chromatography-MS datasets can be extremely useful for quality control, experimental monitoring and knowledge extraction. The importance of imaging in differential analysis of proteomic experiments has already been established through two-dimensional gels and can now be foreseen with MS images. We present M Sight, a new software designed to construct and manipulate MS images, as well as to facilitate their analysis and comparison.
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