Journal
SCHIZOPHRENIA RESEARCH
Volume 75, Issue 1, Pages 135-137Publisher
ELSEVIER
DOI: 10.1016/j.schres.2004.10.006
Keywords
cannabis; first onset psychosis; neurocognition
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A priori cannabis use was recorded at index admission for 112 participants in the Manchester first-episode psychosis cohort. 69 of the 100 surviving (mainly schizophrenia) patients were followed up 10-12 years later and assessed on a battery of clinical, behavioural and neurocognitive measures. Individuals who had not used cannabis before the first episode of illness were generally indistinguishable from cannabis users at follow-up, except that the latter group evinced a marked 'sparing' of neurocognitive functions. These findings are briefly discussed in relation to other casual factors in psychosis. (c) 2004 Elsevier B.V. All rights reserved.
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