Journal
PARKINSONISM & RELATED DISORDERS
Volume 11, Issue 4, Pages 247-252Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2005.01.006
Keywords
Parkinson's disease; deep brain stimulation; weight; obesity
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A retrospective chart review characterizing changes in 17 male and 10 female Parkinson's disease (PD) patients undergoing deep brain stimulation (DBS) surgery indicated that 6 mo before surgery, patients lost a mean of 5.1 lbs, whereas in the 6 mo after surgery, subjects gained a mean of 10.1 lbs; 22% gained more than 14 lbs. In 10 patients followed an additional 6 mo, weight gain continued. This weight gain may be associated with decreased energy expenditure due to subsidence of chronic tremor. The magnitude of gain underscores the need for proactive management of body weight in PD patients undergoing DBS. (c) 2005 Elsevier Ltd. All rights reserved.
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