Journal
DEVELOPMENTAL CELL
Volume 8, Issue 6, Pages 803-816Publisher
CELL PRESS
DOI: 10.1016/j.devcel.2005.05.007
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The neuron is a prime example of a highly polarized cell. It is becoming clear that conserved protein complexes, which have been shown to regulate polarity in such diverse systems as the C. elegans zygote and mammalian epithelia, are also required for neuronal polarization. This review considers the role of these polarity proteins in axon specification and synapto-genesis.
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