Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 15, Issue 3, Pages 324-330Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2005.05.007
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Self-splicing group I introns have served as a model for RNA catalysis and folding for over two decades. New three-dimensional structures now bring the details into view. Revelations include an unanticipated turn in the RNA backbone around the guanosine-binding pocket. Two metal ions in the active site coordinate the substrate and phosphates from all three helical domains.
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