Journal
PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
Volume 272, Issue 1568, Pages 1171-1177Publisher
ROYAL SOC
DOI: 10.1098/rspb.2004.3020
Keywords
dengue; urban epidemics; heterogeneous models; Easter Island; Brazil
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The importance of spatial heterogeneity and spatial scales (at a village or neighbourhood scale) has been explored with individual-based models. Our reasoning is based on the Chilean Easter Island (EI) case, where a first dengue epidemic occurred in 2002 among the relatively small population localized in one village. Even in this simple situation, the real epidemic is not consistent with homogeneous models. Conversely, including contact heterogeneity on different scales (intra-households, inter-house, inter-areas) allows the recovery of not only the El epidemiological curve but also the qualitative patterns of Brazilian urban dengue epidemic in more complex situations.
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