Journal
ORGANIC LETTERS
Volume 7, Issue 12, Pages 2501-2504Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol050897a
Keywords
-
Categories
Funding
- NIGMS NIH HHS [GM56062, R01 GM056062] Funding Source: Medline
Ask authors/readers for more resources
A regioselective synthesis of propargylamines by the coupling of propargyl alcohols with tosylamines and carbamates catalyzed by an air and moisture-tolerant rhenium-oxo complex is described. The ability to couple functionalized components allows for convergent approaches to nitrogen-containing heterocyclic compounds such as the marine antibiotic pentabromopseudilin. These compounds were assayed against human lipoxygenase and found to be both potent and selective.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available