Journal
EXPERIMENTAL CELL RESEARCH
Volume 306, Issue 2, Pages 336-342Publisher
ELSEVIER INC
DOI: 10.1016/j.yexcr.2005.03.019
Keywords
hedgehog signalling; Zebrafish; muscle cell; Blimp1; slow twitch fibre
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Signalling by members of the Hedgehog family of secreted proteins plays a central role in the development of many animal species. In the zebrafish embryo, the specification of myoblast fates is controlled by Hedgehog signals emanating from axial midline structures. Distinct muscle cell identities are induced by varying levels of signalling activity. The SET domain transcription factor, Blimp I, is a key target of Hedgehog signalling in this process. (c) 2005 Elsevier Inc. All rights reserved.
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