Journal
SCIENCE
Volume 308, Issue 5728, Pages 1589-1592Publisher
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.1112063
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Funding
- NCI NIH HHS [CA 016672] Funding Source: Medline
- NICHD NIH HHS [HD046226, HD046282] Funding Source: Medline
- NIEHS NIH HHS [ES 07784, ES08263] Funding Source: Medline
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Uterine fibroids (leiomyomas) have historically been viewed as important chiefly as the major indication for hysterectomy. As new therapies are developed, the heterogeneity of this disease becomes therapeutically relevant. An awareness of the role of genetics, the extraceilular matrix, and hormones in tumor etiology is key to understanding this disease.
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