Journal
CARBOHYDRATE RESEARCH
Volume 340, Issue 8, Pages 1563-1565Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2005.03.009
Keywords
2-O-(2-hydroxybutyl)cyclomaltoheptaose; 2-O-(2-hydroxybutyl)-beta-cyclodextrin; capillary electrophoresis (CE); chiral selector
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A new soluble cyclornaltoheptaose (cyclodextrin) derivative, 2-O-(2-hydroxybutyl)cyclomaltoheptaose [2-O-(2-hydroxybutyl)-beta-cyclodextrin, 2-HB-beta-CD], was prepared and studied as an efficient chiral selector in the separation of racemic mixtures of drugs by capillary electrophoresis (CE). Results showed that 2-HB-beta-CD could provide higher separating capability than that of P-CD and the similarly substituted 2-HP-beta-CD. (c) 2005 Elsevier Ltd. All rights reserved.
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