Journal
TETRAHEDRON
Volume 61, Issue 24, Pages 5889-5894Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2005.03.138
Keywords
N-,S or C-cyanation; electrophilic cyanating agent; 2-Cyanopyridazin-3(2H)-ones
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2-Cyanopyridazin-3(2H)-ones are novel, effective, selective and electrophilic cyanating agents. A variety of amino, thiol and carbon nucleophiles are chemoselectively N-, S- or C-cyanated in excellent yield using 2-cyanopyridanzin-3(2H)-ones in water or tetrahydrofuran. (c) 2005 Elsevier Ltd. All rights reserved.
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