Journal
BIOINFORMATICS
Volume 21, Issue 12, Pages 2912-2913Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti434
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The availability of advanced profile-profile comparison tools, such as PRC or HHsearch demands sophisticated visualization tools not presently available. We introduce an approach built upon the concept of HMM logos. The method illustrates the similarities of pairs of protein family profiles in an intuitive way. Two HMM logos, one for each profile, are drawn one upon the other. The aligned states are then highlighted and connected.
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