Journal
ORGANIC LETTERS
Volume 7, Issue 13, Pages 2731-2734Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol050901i
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- NCI NIH HHS [CA44848] Funding Source: Medline
- NCRR NIH HHS [S10RR017768] Funding Source: Medline
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Analysis of the fermentation broth of a strain of the marine actinomycete Salinispora tropica has led to the isolation of two unprecedented macrolides, sporolides A (1) and B (2). The structures and absolute stereochemistries of both metabolites were elucidated using a combination of NMR spectroscopy and X-ray crystallography.
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