Journal
THEORETICAL POPULATION BIOLOGY
Volume 68, Issue 1, Pages 41-53Publisher
ACADEMIC PRESS INC ELSEVIER SCIENCE
DOI: 10.1016/j.tpb.2005.02.001
Keywords
coalescent process; importance sampling; migration; stepwise mutation
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An importance sampling algorithm for computing the likelihood of a sample of genes at loci under a stepwise mutation model in a subdivided population is developed. This allows maximum likelihood estimation of migration rates between subpopulations. The time to the most recent common ancestor of the sample can also be computed. The technique is illustrated by an analysis of a data set of Australian red fox populations. (c) 2005 Elsevier Inc. All rights reserved.
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