Journal
NATURAL PRODUCT RESEARCH
Volume 19, Issue 5, Pages 529-539Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/14786410512331330558
Keywords
neem; azadirachtin-A; antifeedancy; Spodoptera litura
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Azadirachtin-A (Aza-A, figure 1) was subjected to a variety of synthetic transformations and the antifeedant activity and toxicity of the azadirachtin derivatives were assessed against second instar larvae Spodoptera litura on castor leaves in comparison with the crude material containing 9.14% Aza-A, as well as relatively pure 91% Aza-A. A probable mechanism for the base initiated fragmentation of the diketocarbonate into a decalin fragment and a spiroketal moiety has been proposed. The present study indicates that the combination of insect toxicity and antifeedancy of azadirachtin provides good crop protection.
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