Journal
MOLECULAR PHARMACEUTICS
Volume 2, Issue 4, Pages 264-272Publisher
AMER CHEMICAL SOC
DOI: 10.1021/mp050020d
Keywords
micelle; drug delivery; dendrimers; controlled release; targeted delivery; polymer-drug conjugates
Funding
- National Institutes of Health
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This review highlights the developments in dendrimer-based micelles for drug delivery. Dendrimers, the perfectly branched monodisperse macromolecules, have certain structural advantages that make them attractive candidates as drug carriers for controlled release or targeted delivery. As polymeric micelle-based approaches precede the work in dendrimers, these are also discussed briefly. The review concludes with a perspective on possible applications of biaryl-based dendrimeric micelles that exhibit environment-dependent conformations, in drug delivery.
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