Journal
CATALYSIS COMMUNICATIONS
Volume 6, Issue 7, Pages 455-458Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.catcom.2005.04.003
Keywords
heterogeneous catalysis; fluorapatite; metal halide; 3,4-dihydropyrimidin-2-one
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The fluorapatite doped with metal halide (ZnCl2, CuCl2 and NiCl2) catalyses the three-component Biginelli reaction to afford the corresponding dihydropyrimidin-2-ones in high yields. This heterogeneous catalysis has been carried out in liquid phase using ethanol as solvent. (C) 2005 Elsevier B.V. All rights reserved.
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