Journal
CLINICAL INFECTIOUS DISEASES
Volume 41, Issue 1, Pages 118-121Publisher
OXFORD UNIV PRESS INC
DOI: 10.1086/430829
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We reviewed all of the published reports of cases of fluoroquinolone treatment failures for respiratory tract infection due to fluoroquinolone-resistant Streptococcus pneumoniae. There were 20 ciprofloxacin and levofloxacin treatment failures reported. Physicians should be aware, when treating pneumococcal respiratory tract infections in older patients with a fluoroquinolone, that clinical failures might occur, especially for patients with comorbid illnesses and a history of recent fluoroquinolone use.
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