Journal
JOURNAL OF ANTIBIOTICS
Volume 58, Issue 7, Pages 460-467Publisher
JAPAN ANTIBIOTICS RESEARCH ASSOC
DOI: 10.1038/ja.2005.61
Keywords
antimycin; antifungal activity; new antibiotic; Streptomyces
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Seven new antimycin antibiotics, named antimycins A(10), A(11), A(12), A(13), A(14), A(15) and A(16), were isolated from the fermentation broth of strains of Streptomyces spp. SPA-10191 and SPA-8893, along with known antimycins A(1), A(2), A(3) and A(4). The structures of the new antimycins were determined by spectral analyses, including 2D NMR techniques. These compounds exhibited antifungal activity against Candida utilis.
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