Journal
SMALL
Volume 1, Issue 7, Pages 688-692Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.200500087
Keywords
drug delivery; fluorescent probes; microencapsulation; microfluids; microparticles
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The Flow Focusing platform is especially advantageous for micro- and nanoparticle production. This versatile technique is amenable to designing the size, surface treatment and internal topology of the particles; mechanical stresses are minimal-an optimal feature for the manipulation of delicate substances. Multiplexing and high-rate production are readily implemented. Adaptive operational design can lead, in one single step, to finely tuned microcapsules encasing different products within a targeted morphology. This achievement is of great significance for most microcapsule applications in the biosciences (for example, drug delivery, cell encapsulation, and the production of bead arrays).
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