Journal
VETERINARY JOURNAL
Volume 170, Issue 1, Pages 84-90Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.tvjl.2004.04.004
Keywords
cat; injection-site sarcoma; doxorubicin; surgery
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Sixty-nine cats were treated for injection-site sarcomas at the Veterinary Teaching Hospital of Grugliasco, Turin (Italy). The animals were divided into two subgroups: those subjected to four doxorubicin cycles combined with radical surgical excision 10 days after the second chemotherapy cycle (group A, 49 cats) or those treated with surgery alone (group 13, 20 cats). Each cat was monitored for lung metastasis and local recurrence. In group A, 28 cats were alive at the end of the follow-up period. In this group, the recurrence rate was 40.8% while lung metastasis occurred in 12% of cats. In group B, eight animals were alive at the end of the follow-up period, while the rates of recurrence and metastasis were 35% and 10%. Neither the median disease-free interval nor the median overall survival was reached in either group. Moreover, there were no statistically significant differences between the two groups. (c) 2004 Elsevier Ltd. All rights reserved.
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