Journal
INTERNATIONAL JOURNAL OF CLINICAL PRACTICE
Volume 59, Issue 7, Pages 777-781Publisher
WILEY
DOI: 10.1111/j.1742-1241.2005.00477.x
Keywords
Behcet's disease; endothelial dysfunction; flow-mediated dilation; carotid artery intima-media thickness
Ask authors/readers for more resources
Brachial artery endothelial dysfunction was shown previously in a small group of Behcet's disease (BD) patients. This study aimed to compare the endothelial function in BD patients with and without vascular involvement. The study group consisted of 25 BD patients with vascular involvement, 25 BD patients without any vascular disease and 46 healthy controls. Brachial artery flow-mediated (endothelium-dependent) dilation (FMD), nitroglycerine-induced dilation and carotid artery intima-media thickness were measured. FMD was impaired in patients with BD (10.41 +/- 3.85%) compared to healthy controls (14.41 +/- 3.39%, p < 0.001). FMD was significantly lower in BD patients with vascular involvement (8.80 +/- 3.63%) than those without any vascular disease (12.02 +/- 3.43%, p = 0.003). This study reveals that endothelial dysfunction documented by brachial artery FMD is a feature of BD, and it is more prominent in patients with vascular involvement.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available