Comparative study of structure-activity relationship of Di and triorganotin (IV) complexes of monomethyl glutarate

A series of di and triorganotin(IV) complexes of monomethyl glutarate have been synthesized and characterized through H-1 C-13 Sn-119 NMR, FT-IR and Sn-119 Mossbauer spectroscopy. On the basis of these techniques, it is proposed that the ligand molecule is bound to the tin atom through the carbonyl oxygen. The data reveal that diorganotin(IV) complexes exhibit hexa-coordination with octahedral geometry, while triorganotin(IV) complexes have penta-coordination with trigonal bipyramidal geometry. Biological evaluation against various microorganisms indicate that diorganotin(IV) complexes are less active than the triorganotin(IV) complexes.