Journal
BRITISH JOURNAL OF HAEMATOLOGY
Volume 130, Issue 2, Pages 271-275Publisher
WILEY
DOI: 10.1111/j.1365-2141.2005.05586.x
Keywords
graft-versus-host disease; extracorporeal photochemotherapy; ultraviolet; stem cell transplantation; bone marrow
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Recent studies suggest that extracorporeal photochemotherapy (ECP) may be beneficial in patients with steroid-refractory chronic graft-versus-host disease (cGvHD). However, it is not yet clear whether certain conditions, such as age, mode of onset of cGvHD etc., influence clinical response and whether certain affected organs are more sensitive to ECP than others. We analysed the main clinical and laboratory parameters related to evolution of the disease in 32 steroid-refractory cGvHD patients, to identify any useful response predictors to ECP. ECP affected the course of the disease positively in 78% (25/32) of our cases.
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