Journal
JOURNAL OF THE ACOUSTICAL SOCIETY OF AMERICA
Volume 118, Issue 1, Pages 539-550Publisher
ACOUSTICAL SOC AMER AMER INST PHYSICS
DOI: 10.1121/1.1923367
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Zero-thickness interface models are developed to describe the encapsulation of microbubble contrast agents. Two different theological models of the interface, Newtonian (viscous) and viscoelastic, with theological parameters such as surface tension, surface dilatational viscosity, and surface dilatational elasticity are presented to characterize the encapsulation. The models are applied to characterize a widely used microbubble based ultrasound contrast agent. Attenuation of ultrasound passing through a solution of contrast agent is measured. The model parameters for the contrast agent are determined by matching the linearized model dynamics with measured attenuation data. The models are investigated for its ability to match with other experiments. Specifically, model predictions are compared with scattered fundamental and subharmonic responses. Experiments and model prediction results are discussed along with those obtained using an existing model [Church, J. Acoust. Soc. Am. 97, 1510 (1995) and Hoff et al., J. Acoust. Soc. Am. 107, 2272 (2000)] of contrast agents. (c) 2005 Acoustical Society of America.
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