Journal
CHEST
Volume 128, Issue 1, Pages 370-381Publisher
ELSEVIER
DOI: 10.1378/chest.128.1.370
Keywords
DNA repair; estrogen receptor; human papilloma virus; non-small cell lung cancer; sex; small cell lung cancer
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Lung cancer is the major cause of cancer-related death in both men and women in the United States. Emerging evidence indicates that there are differences in the pathogenesis and possibly increased susceptibility to lung cancer in women. In addition, considerable data support small, but important differences favoring women in terms of response to therapy and long-term survival after the diagnosis of lung cancer, regardless of histology or stage. These differences in both biology and outcome will be important considerations in the design of future trials of screening and therapy for lung cancer.
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