Journal
ORGANIC LETTERS
Volume 7, Issue 14, Pages 3053-3056Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol051040g
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Funding
- NIGMS NIH HHS [GM-28961, R01 GM028961] Funding Source: Medline
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The development of an approach leading to the total synthesis of dactylolide is described. The key features of this route include a catalytic asymmetric allylation, a diastereoselective pyran annulation, and a Horner-Wadsworth-Emmons macrocyclization.
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