Journal
NEURON
Volume 47, Issue 1, Pages 13-28Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2005.05.019
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The Mauthner (M) cell is a critical element in a vital escape reflex triggered by abrupt or threatening events. Its properties at the molecular and synaptic levels, their various forms of plasticity, and the design of its networks, are all well adapted for this survival function. They guarantee that this behavior is appropriately unilateral, variable, and unpredictable. The M cell sets the behavioral threshold, and, acting in concert with other elements of the brainstem escape network, determines when, where, and how the escape is executed.
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