Journal
OPTICS EXPRESS
Volume 13, Issue 14, Pages 5483-5493Publisher
OPTICAL SOC AMER
DOI: 10.1364/OPEX.13.005483
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Funding
- NCI NIH HHS [R01 CA103769-02, R33 CA110130-01, R01 CA103769, R33 CA110130] Funding Source: Medline
- NCRR NIH HHS [R01 RR019768-02] Funding Source: Medline
- NHLBI NIH HHS [R01 HL070039, R01 HL070039-02, R01 HL076398, R01 HL076398-03] Funding Source: Medline
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Phase-resolved Doppler optical coherence tomography has been used to image blood flow dynamics in various tissues using both time-domain and spectral-domain optical coherence tomography techniques. In this manuscript, we present phase-resolved Doppler imaging with a highspeed optical frequency domain imaging system. We demonstrate that by correcting for spurious timing-induced phase errors, excellent flow sensitivity can be achieved, limited only by the imaging signal-to-noise ratio. Conventional and Doppler images showing flow in an Intralipid phantom and in human skin are presented. Additionally, we demonstrate the ability of phase-resolved OFDI to measure high flow rates without the deleterious effects of fringe washout. (C) 2005 Optical Society of America.
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