Journal
BIOINFORMATICS
Volume 21, Issue 14, Pages 3164-3165Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bti481
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Funding
- NIGMS NIH HHS [GM068278] Funding Source: Medline
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TAMO ( Tools for Analysis of MOtifs) is an object-oriented computational framework for interpreting transcriptional regulation using DNA-sequence motifs. To simplify the application of multiple motif discovery programs to genome-wide data, TAMO provides a sophisticated motif object with interfaces to several popular programs. In addition, TAMO provides modules for integrating motif analysis with diverse data sources including genomic sequences, microarrays and various databases. Finally, TAMO includes tools for sequence analysis, algorithms for scoring, comparing and clustering motifs, and several useful statistical tests. Recently, we have applied these tools to analyze tens of thousands of motifs derived from hundreds of microarray experiments.
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