METHOX:: A new pyridine N-oxide organocatalyst for the asymmetric allylation of aldehydes with allyltrichlorosilanes

Allylation of aromatic aldehydes with allyltrichlorosilane is catalyzed by the new terpene-derived pyridine N-oxide (+)-METHOX (<= 5 mol %) in MeCN with high enantioselectivities (<= 96% ee) and conversion rates; this catalyst retains high selectivity even at room temperature.