Journal
ORGANIC LETTERS
Volume 7, Issue 15, Pages 3243-3246Publisher
AMER CHEMICAL SOC
DOI: 10.1021/ol051024j
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An operationally simple and recoverable fluorous CBS methodology was developed. The in situ-generated fluorous oxazaborolidine efficiently catalyzed the reduction of ketones with high enantioselectivity and reactivity. The subsequent recycling of the fluorous prolinol precatalyst was achieved by fluorous solid-phase extraction.
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