Journal
JOURNAL OF ORGANIC CHEMISTRY
Volume 70, Issue 15, Pages 6126-6128Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jo050760y
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Alkynyldimethylaluminum reagents react with various aromatic and aliphatic acid chlorides in a fast and efficient way. This reaction provides a simple entry to numerous ynones, using readily available, inexpensive, and nontoxic metalating agent, and does not require any transition metal as a catalyst.
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