4.4 Article

Selective capture of Salmonella enterica serovar Typhi genes expressed in macrophages that are absent from the Salmonella enterica serovar Typhimurium genome

Journal

INFECTION AND IMMUNITY
Volume 73, Issue 8, Pages 5217-5221

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/IAI.73.8.5217-5221.2005

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Funding

  1. NIAID NIH HHS [AI24533, R01 AI024533] Funding Source: Medline

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Thirty-six Salmonella enterica serovar Typhi-specific genes, absent from the Salmonella enterica serovar Typhimurium genome, that were expressed in human macrophages were identified by selective capture of transcribed sequences. These genes are located on 15 unique loci of the serovar Typhi genome, including Salmonella pathogenicity islands (SPI-7, SPI-8, and SPI-10) and bacteriophages (ST15, ST18, and ST35).

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