Journal
CURRENT OPINION IN CELL BIOLOGY
Volume 17, Issue 4, Pages 345-352Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.ceb.2005.06.004
Keywords
-
Categories
Ask authors/readers for more resources
Cargo proteins exiting the endoplasmic reticulum en route to the Golgi are typically carried in 60-70 nm vesicles surrounded by the COPII protein coat. Some secretory cargo assemblies in specialized mammalian cells are too large for transport within such carriers. Recent studies on procollagen-I and chylomicron trafficking have reached conflicting conclusions regarding the role of CON proteins in ER exit of these large biological assemblies. COPII is no doubt essential for such transport in vivo, but it remains unclear whether COPII envelops the membrane surrounding large cargo or instead plays a more indirect role in transport carrier biogenesis.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available