4.6 Article

Simple and efficient synthesis of 2,7-difunctionalized-1,8-naphthyridines

Journal

MOLECULES
Volume 10, Issue 8, Pages 929-936

Publisher

MOLECULAR DIVERSITY PRESERVATION INTERNATIONAL
DOI: 10.3390/10080929

Keywords

naphthyridines; 2,7-difunctionalized-1,8-naphthyridines; 2,7-diamino-1,8-naphthyridine

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The syntheses in good yields of some new difunctionalized 1,8-naphthyridines 4, 6, 8 and 9 and a novel triethylene glycol ether-linked dinaphthyridine, 10a, along with the mononaphthyridine-linked ether alcohol 10b are described. An improved and milder method for the synthesis of 2,7-diamino-1,8-naphthyridine (14) is also reported.

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