Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 78, Issue 12, Pages 4516-4518Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.07974-11
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- European Space Agency ESA/ESTEC through the PRODEX
- Belgian Science Policy through the MESSAGE-1 project agreement
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Acetone carboxylase (Acx) is a key enzyme involved in the biodegradation of acetone by bacteria. Except for the Helicobacteraceae family, genome analyses revealed that bacteria that possess an Acx, such as Cupriavidus metallidurans strain CH34, are associated with soil. The Acx of CH34 forms the heterohexameric complex alpha(2)beta(2)gamma(2) and can carboxylate only acetone and 2-butanone in an ATP-dependent reaction to acetoacetate and 3-keto-2-methylbutyrate, respectively.
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