Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 78, Issue 19, Pages 7132-7136Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.01624-12
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- Leibniz Graduate School-Systems Biology Lab-on-a-Chip (S-BLOC)
- European Union (EFRE)
- Ministry of Innovation, Science, Research, and Technology of North-Rhine Westphalia
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Singularized cells of Pichia pastoris, Hansenula polymorpha, and Corynebacterium glutamicum displayed specific growth rates under chemically and physically constant conditions that were consistently higher than those obtained in populations. This highlights the importance of single-cell analyses by uncoupling physiology and the extracellular environment, which is now possible using the Envirostat 2.0 concept.
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