Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 78, Issue 8, Pages 3028-3032Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.06920-11
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Funding
- Microbiology across Campuses Educational and Research Venture (M-CERV)
- AgResearch at The University of Tennessee
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Culture-independent sampling in conjunction with a functional cloning approach identified diverse antibiotic resistance genes for different classes of antibiotics in gut microbiomes from both conventionally raised and free-range chickens. Many of the genes are phylogenetically distant from known resistance genes. Two unique genes that conferred ampicillin and spectinomycin resistance were also functional in Campylobacter, a distant relative of the Escherichia coli host used to generate the genomic libraries.
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