Journal
AMINO ACIDS
Volume 29, Issue 2, Pages 89-100Publisher
SPRINGER WIEN
DOI: 10.1007/s00726-005-0212-y
Keywords
Beta-amino acid; Medicinal Chemistry; antifungal; cispentacin; icofungipen; asymmetric synthesis
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The structural element of alicyclic beta-amino acids shows some remarkable biological effects: For some 5- and 6-membered beta-amino acids a unique anti fungal activity has been observed, 7-membered beta-amino acid derivatives have been investigated for neurological disorders. The application of 5-, 6- and 7-membered alicyclic beta-amino acids in Medicinal Chemistry will be reported.
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