Journal
JOURNAL OF BACTERIOLOGY
Volume 187, Issue 15, Pages 5486-5492Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.187.15.5486-5492.2005
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Funding
- NIAID NIH HHS [AI057451, R01 AI057451] Funding Source: Medline
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Staphylococcus aureus expresses various cell wall-associated and extracellular virulence factors, coordinately controlled by different two-component signal transduction systems and transcriptional regulators. In this study, we used microarray technology to identify the genes regulated by ArlR. The microarray data indicate that ArlR functions as a positive regulator and also as a negative repressor to directly and/or indirectly mediate the expression of at least 114 genes involved in different functions, including autolysis, cell division, growth, and pathogenesis.
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