Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 77, Issue 11, Pages 3892-3895Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02941-10
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- Danish National Advanced Technology Foundation
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Nanoparticle complexes were prepared from chitosans of various molecular weights (MW) and degrees of deacetylation (DD). The antimicrobial effect was assessed by the Live/Dead BacLight technique in conjunction with confocal scanning laser microscopy (CSLM) and image analysis. Nanocomplexes prepared from chitosans with high MW showed a low antimicrobial effect (20 to 25% of cells damaged), whereas those prepared from low-MW chitosans showed high antimicrobial effect (>95% of cells damaged).
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