Journal
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
Volume 180, Issue 8, Pages 1849-1862Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/104265090889512
Keywords
condensation; cyclisation using sodium diselenide; dehydroxychlorination; esterification; hydrolysis; Vilsmeier-Haack Reaction
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The compounds selenolo(2,3-b)quinoline-2-carboxylic ethyl esters were synthesized in good yields by the reaction of 3-(2-chloro-3-quinolyl)actylic ethyl esters, with the nucleophilic reagent sodium diselenide in ethanol medium under a nitrogen atmosphere. Cytogenetic studies on human blood leucocytes in vitro were evaluated for some of the synthesized compounds. Most of the synthesized compounds were tested for their antibacterial and antifungal activities.
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