Journal
SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE
Volume 26, Issue 4, Pages 417-428Publisher
THIEME MEDICAL PUBL INC
DOI: 10.1055/s-2005-916157
Keywords
pulmonary arterial hypertension; congenital heart disease; pulmonary thromboendarterectomy; lung and heart-lung transplantation; atrial septostomy
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Surgical and interventional therapies for pulmonary arterial hypertension (PAH) in appropriately selected patients have the potential to dramatically improve or, in some cases, cure PAH. These include atrial septostomy, a palliative procedure or bridge to transplantation in patients with refractory right heart failure, pulmonary thromboendarterectomy for pulmonary hypertension associated with chronic thromboembolic disease, and closure of congenital systemic-pulmonary shunts in patients with PAH but without significant pulmonary vascular disease. Lung transplantation should be considered for patients with all forms of PAH who demonstrate advanced or progressive disease.
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