Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 76, Issue 15, Pages 5321-5326Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.00323-10
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- University of Minnesota Academic Health Center [07-16]
- USDA
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Functional metagenomics was used to search for florfenicol resistance genes in libraries of cloned DNA isolated from Alaskan soil. A gene that mediated reduced susceptibility to florfenicol was identified and designated pexA. The predicted PexA protein showed a structure similar to that of efflux pumps of the major facilitator superfamily.
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