Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 76, Issue 2, Pages 622-626Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02097-09
Keywords
-
Categories
Funding
- BMVEL/FNR [FKZ 22015806, 06NR158]
Ask authors/readers for more resources
We have developed the conversion of glycerol into thermoplastic poly(3-hydroxypropionate) [poly(3HP)]. For this, the genes for glycerol dehydratase (dhaB1) of Clostridium butyricum, propionaldehyde dehydrogenase (pduP) of Salmonella enterica serovar Typhimurium LT2, and polyhydroxyalkanoate (PHA) synthase (phaC1) of Ralstonia eutropha were expressed in recombinant Escherichia coli. Poly( 3HP) was accumulated up to 11.98% (wt/wt [cell dry weight]) in a two-step, fed-batch fermentation. The present study shows an interesting application to engineer a poly( 3HP) synthesis pathway in bacteria.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available