Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 75, Issue 9, Pages 2936-2939Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02524-08
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Funding
- Center for Aseptic Processing and Packaging (CAPPS)
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This paper describes a molecular-based method which is able to discriminate between viable and inactivated Bacillus subtilis spores by utilizing the DNA-intercalating dye propidium monoazide. The approach should be valuable in our attempt to employ molecular methods to streamline the evaluation of process validation using bacterial endospores.
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