Journal
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
Volume 75, Issue 6, Pages 1750-1753Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/AEM.02279-08
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- Colgate-Palmolive
- M. J. Murdock Charitable Trust
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The diffusive penetration of fluorescently tagged macromolecular solutes into model oral biofilms was visualized by time-lapse microscopy. All of the solutes tested, including dextrans, proteases, green fluorescent protein, and immunoglobulin G, accessed the interior of cell clusters 100 to 200 mu m in diameter within 3 min or less.
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