Journal
CURRENT OPINION IN STRUCTURAL BIOLOGY
Volume 15, Issue 4, Pages 435-440Publisher
CURRENT BIOLOGY LTD
DOI: 10.1016/j.sbi.2005.06.002
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Funding
- Biotechnology and Biological Sciences Research Council [B19845] Funding Source: researchfish
- Biotechnology and Biological Sciences Research Council [B19845] Funding Source: Medline
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Proteins and lipids make sense in rational approaches to the design of systems for the study of membrane proteins. Lipids surround integral membrane proteins in their natural environment. Although lipids have always formed part of investigations into membrane proteins, it has generally been the proteins themselves that have taken the limelight. As knowledge of membrane proteins has increased, so has that of their interactions with lipids. This increased understanding of the interplay of proteins and lipids, together with existing knowledge of lipid properties, is enabling new approaches to be introduced for membrane protein study. The lipids can be used to control protein behaviour and as novel probes of protein motion.
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